It shows antibody therapy markedly ameliorated the disease, concurring with earlier mucosal immunology and pathophysiologic studies. The discrimination potential is optimized by analyzing data with curve fitting. Interleukin-10 knockout mouse model of the diseases with anti-TNFα treatment was used. Understanding the therapeutic response includes the analysis of absorption bands representing constituent molecules. This study presents an application of infrared spectroscopy of sera for monitoring the efficacy of anti-TNFα therapy for inflammatory bowel diseases.
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